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FDA Approves Semaglutide for Chronic Kidney Disease and Heart Health in Diabetes Patients

Posted on 3/21/2025 by Schuyler Traudt
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Semaglutide, a medication originally developed to treat type 2 diabetes and obesity, has received approval from the U.S. FDA for additional benefits related to chronic kidney disease (CKD) and heart health. This approval marks a significant milestone as semaglutide becomes the first treatment in its class, known as GLP-1 receptor agonists, to be approved for patients with type 2 diabetes and CKD.

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Semaglutide’s New Indications: The FDA’s approval is based on a late-stage clinical study showing that semaglutide can help reduce the risk of death from chronic kidney disease and decrease the occurrence of major cardiovascular events, such as heart attack and stroke. The medication was shown to reduce the risk of death and cardiac events by 24%.

Why This Matters: Chronic kidney disease (CKD) affects about 37 million adults in the U.S., and approximately 40% of people with type 2 diabetes also experience kidney complications. This new approval opens up a treatment option for those who need additional support in managing both their diabetes and kidney health.

Expanding Beyond Diabetes: Semaglutide is also approved to reduce the risk of heart-related events in people with diabetes and heart disease. Additionally, Novo Nordisk is exploring semaglutide’s potential for other conditions, including Alzheimer’s disease and fatty liver disease, which could further expand its benefits beyond diabetes and weight management.

What’s Next for Semaglutide: With ongoing studies and approvals, semaglutide is proving to be a versatile and impactful treatment for various health conditions. As it becomes more widely available, it may offer significant health improvements for individuals with type 2 diabetes, chronic kidney disease, and cardiovascular risks.

For more information, check out the source article here.

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